CzbnAuto® Autologous Cardiac Stem Cells
Product Specifications
| ID | Product Specifications | Product Name |
|---|---|---|
| Czbn-ASC012 | 0.1-2×10⁸ | CzbnAuto® Autologous Cardiac Stem Cells |
Stem Cell Attributes
Cardiac tissue mesenchymal stem cells.
Core Features
Multi-lineage differentiation
Differentiate into cardiomyocytes, vascular endothelial cells, and vascular smooth muscle cells in vitro; difficult to generate large quantities of mature, functional cardiomyocytes in vivo.
Paracrine Protection (Primary Mechanism of Action)
Secrete cytokines and exosomes; inhibit cardiomyocyte apoptosis, reduce myocardial inflammation, suppress ventricular remodeling, and improve the myocardial microenvironment.
Microvascular Regeneration
Promotes neovascularization in the myocardial infarction region to improve blood supply to ischemic myocardium.
Transform Application Research Directions
Research on Repair of Acute Myocardial Infarction (AMI)
Research focuses on differentiation into cardiomyocytes and vascular endothelial cells to promote myocardial regeneration and angiogenesis, reduce infarct size, improve cardiac contractility, and rescue濒死 myocardium.
Research on Improvement and Repair in Chronic Heart Failure (HF)
Explore promoting cardiomyocyte regeneration, improving cardiac pump function and exercise tolerance, enhancing quality of life, and investigating potential long-term prognostic benefits.
Vascular Repair and Myocardial Protection in Ischemic Heart Disease (Coronary Artery Disease)
Promotes repair of damaged vascular endothelium and establishment of collateral circulation, alleviates myocardial ischemia symptoms, protects ischemic myocardium from further injury, and helps relieve angina.
Intervention studies in non-ischemic cardiomyopathy
Promote differentiation into cardiomyocytes to replenish damaged and reduced cells, enhance cardiac contractility, and improve symptoms of cardiac enlargement and heart failure. Research focuses on regulating cardiomyocyte metabolism to inhibit hypertrophy progression and improve diastolic function (e.g., in dilated or hypertrophic cardiomyopathy).
Prevention and Intervention for Individuals at High Risk of Cardiovascular Disease
Research focuses on improving endothelial function, regulating lipid metabolism, and reducing inflammation to explore preventive repair and protection of the cardiovascular system, thereby lowering disease risk.
Functional Recovery in Cardiovascular Rehabilitation
Explore recovery-phase interventions post-acute treatment to promote myocardial repair, improve vascular function, restore cardiac function, enhance exercise tolerance, and improve quality of life.
Why Choose Chunzhu: The Century-Long Life Bank
Third-generation iPSC small-molecule transdifferentiation technology derived from Nobel Prize-winning research
- No gene editing involved, ensuring greater safety.
- Autologous cardiac stem cells derived from blood cell reprogramming
- Capable of cardiac lineage-directed differentiation, suitable for cardiovascular injury repair.
Six Core Advantages
- Draw 80-150 ml of blood; complete library construction within 6-10 days.
- Autologous cell source with low risk of immune rejection and no gene editing involved.
- Store for all ages; produce functional cells on demand
Empowering the Human Genetic Resources Platform
- Platform inbound management, end-to-end sample monitoring and traceability
- Companion AI health simulation and clinical reference plans
Cooperative Consortium of the Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences
- Sync cutting-edge research findings
- Accelerate technology iteration and clinical research advancement
End-to-end workflow: Preparation · Storage · Tertiary Hospital Clinical Integration
- Beyond just storing cells, we enable seamless access and usage.
- Support future clinical translation and implementation
Three steps to storage
Blood Collection and Sampling
80-150ml blood sample collection
GMP Laboratory Library Preparation
Cell preparation and library construction completed in 6-10 days
-196°C Liquid Nitrogen Long-Term Deep-Freeze Storage
Long-term storage and on-demand production of targeted functional cells